Two studies in the New England Journal of Medicine show colonoscopy?s value in detecting colorectal cancer and reducing mortality.
In one, some 2600 patients with adenomatous polyps had them removed during colonoscopy. After a median follow-up of 16 years, colorectal cancer mortality was some 50% lower in that group, compared with a control group based on the U.S. population. (Similar findings occurred among a group of patients whose polyps were nonadenomatous.)
The other study is an interim report of a long-term comparison between screening with colonoscopy and fecal immunochemical testing. Some 57,000 asymptomatic average-risk adults were randomized to either one-time colonoscopy or immunochemical testing biennially over 10 years. After the colonoscopies and first round of chemical testing, cancer was detected equally in both groups. However, advanced adenomas were more likely to be found among those undergoing colonoscopy.
Editorialists conclude that ?colonoscopy is an effective screening test.? Although patients are more likely to accept chemical testing than colonoscopy, fecal testing ?is not a good test for detecting adenomas.?
Source: NEJM study on colorectal cancer mortality.
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Source: http://zedie.wordpress.com/2012/02/26/polypectomy-confirmed-to-reduce-colorectal-cancer-mortality/
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